Charter on Strategic Partnership between the Government of the United States of America and the Government of the Republic of Azerbaijan: Realities and Challenges, signed in Baku on February 10, 2026, takes relations to a new level. The document covers the areas of regional coordination (energy, trade, transit), economic investments (artificial intelligence and digital infrastructure), defense and security. This study systematically analyzes the economic impact of the Charter on the Azerbaijani economy, digitalization and artificial intelligence, transport corridors (especially the Middle Corridor), and the TRIPP Project (Trump Route for International Peace and Prosperity).